Clinical Intervention and Translation Core

The Clinical Intervention and Translation (CIT) Core provides NORC members assistance with clinical research studies involving modification of body weight, diet, and exercise to evaluate the impact on a range of physiological and behavioral outcomes. The CIT Core takes advantage of experienced Registered Dietician (RD) and nutritionist expertise, Anschutz Health and Wellness Center (AHWC) facilities for state-of-art lifestyle intervention, and the Colorado and Clinical Translational Sciences Institute (CCTSI) Nutrition Core. All services are provided on a fee for service basis (please email

The CIT Core offers the following services to our research base:

Weight Loss and Weight Loss Maintenance Services:

  • Planning, resources, staff, and facilities for weight loss and weight loss maintenance interventions, including comprehensive behavioral support programs delivered by trained interventionalists.
  • Weight loss interventions can be delivered one-on-one or in group/cohort-based settings, with options for in person or virtual delivery.
  • Behavioral weight loss programs can be customized in regard to use of calorie controlled diets and/or meal replacements to achieve weight loss targets of 5-15% over 8-26 weeks.
  • Specialized weight loss curriculum can be developed by registered dietitians to meet study needs.
  • Ongoing behavioral support for weight stability/weight loss maintenance can also be provided.

Metabolic Kitchen/Diet Services:

  • Metabolic meal planning and design, individualized for participant energy needs, food preferences, and study macro- and/or micro-nutrient targets
  • Metabolic meal preparation measurement, and dispensation.
  • Ad libitum feeding
  • Design of specialty foods for targeted dietary interventions

Measurement of Food Intake and Eating Behaviors:

  • Dietary intake assessment – habitual and during protocol interventions
  • Dietary intake can be assessed using traditional self-report tools, photographic food records, or novel passive capture devices
  • Hunger and satiety assessment
  • Assistance with measuring eating-related behaviors and appetite using validated tools and questionnaires

Statistical Support:

  • Can provide statistical support for obesity, nutrition, and metabolism related studies, including power calculations for grant submission and data analysis.

Exercise Interventions:

  • Can provide supervised aerobic or resistance training exercise interventions at the AHWC Fitness Center.

Application of NIH Accumulating Data to Optimally Predict Obesity Treatment (ADOPT) Core Measures:

  • Assist with the implementation of ADOPT Core measures across 4 domains (Biologic, Behavioral, Psychosocial, and Environmental) within weight loss interventional trials.

Clinical/Translational Research Study Design Support:

  • Can assist in the design of clinical studies in the area of obesity, nutrition, and metabolism

View Clinical Intervention and Translation Core Team